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Homeothermic Monitoring System – Temperature Controller Thermostar

See more by: Conduct Science

$1,850.00$1,990.00

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Description

During the process of animal surgery or acute anesthetized animal experiment, maintaining animals’ body temperature is very important for the accuracy and reliability of the results, furthermore, it is an important way to reduce the mortality of the animals. To fulfill this need, we have a new generation of homothermic monitoring system “Thermostar”, which is a closed-loop temperature monitor/control system for rodents. The system includes the control unit, 1 flexible rectal probe, 1 heating pad, and 1 heat insulation pad.

The Homeothermic monitoring system is controlled using a 4.3-inch color LCD touch screen, this user interface allows for a clear view of the subject’s real-time core body temperature, the target temperature, and heating state. Audible alarms can be set to alert the user for abnormalities in the subject’s core body temperature.

ConductScience offers the Homeothermic System.

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Producer: Conduct Science

ConductScience is a company specializing in providing high-quality research equipment, lab supplies, and scientific services for the life sciences community.

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Description

Specifications

Product

Model

Size

Description

Homeothermic Monitoring System – Temperature Controller Thermostar*

CS0001

Cage


Complete System:

1 Homeothermic Control Unit

1 Cage size Heating Pad (RWD-69023)

1 Temperature probe (RWD-69022)

1 Insulation heating pad

Homeothermic Monitoring System – Temperature Controller Thermostar*

CS0002

Rat


Complete System:

1 Homeothermic Control Unit

1 Rat Heating Pad (RWD-69024)

1 Temperature probe (RWD-69022)

1 Insulation heating pad

Homeothermic Monitoring System – Temperature Controller Thermostar*

CS0003

Mouse


Complete System:

1 Homeothermic Control Unit

1 Mouse Heating Pad (RWD-69025)

1 Temperature probe (RWD-69022)

1 Insulation heating pad

*Homeothermic Monitoring System – Temperature Controller  includes the complete system.

Accesories

Product

Model

Size

Description

Heating Pad

CS0004

Cage

12 x 20.5 cm / Cable Length 150 cm

Heating Pad

CS0005

Rat

9.0 x 17.0 cm / Cable Length 150 cm

Heating Pad

CS0006

Mouse

7.0 x 10.0 cm / Cable Length 150 cm

Temperature probe

CS0007

Rats and Mice

Rod diameter: 1.5 mm

Rod length: 30 mm

Cord length: 150 cm

Features

  • A closed-loop system with a rectal probe
  • Easy-to-use color touch screen control
  • Two-channel with independent control
  • Precise and stable control of a subject’s temperature
  • Flexible heating pads, easy to clean,
  • Multiple heating pad sizes are available
  • Audible alarms function
  • Centigrade(℃)and Fahrenheit degree (℉) mode display
  • Real-time display of the working status of the heating pad, and monitor the working state of the channel: idle (IDLE), warning (WARNING), standby (STANDBY), and normal work
  •  Heating range:20-45 ℃, 0.1 ℃ resolution, Degrees Celsius and Fahrenheit can be switched
  •  Power supply: 100-240 V, 50/60 Hz
  •  Control unit size: L205 x W148 x H80 mm
  •  Control unit weight: 1.3 kg
Screen
Channels
System
Heating
Display
Pads
Rectal Probes
Temperature
Homeothermic Monitoring System – Temperature Controller

Advantages

Double channels displayed on UI enables two animals’ surgeries and experiments independently at the same time.

The UI displays a working progress bar of heating pads, and rectal probes working status: Idle, Warning, Standby, and Working

Simultaneous monitoring Heating pads and Rectal Probes data

A corresponding heat insulating pad is underneath every heating pad to prevent temperature loss.

Introduction

The Heat and Temperature controller system, also known as the homeothermic monitoring system, is recurrently used for thermal regulation and monitoring in rodent surgeries. The normal body temperature of rodents ranges between 36.2-37.5ºC, whereas the cages in which they are housed have an ambient temperature of 23-24ºC. This difference in temperatures can result in hypothermia in rodents. Additionally, anesthetization and post-operative recovery from anesthesia can also cause hypothermia in rodents. A heat and temperature controller consisting of a thermal controller, a rectal probe, a heating pad, and a heat insulation pad is used for rodent thermoregulation in research laboratories.

Impaired thermoregulation resulting from general anesthesia during stereotaxic surgeries is the leading cause of hypothermia in rodents. In mammals, including rodents, the variations in core temperature are limited to +/- 0.3oC by the body’s autonomic and behavioral responses. This narrow temperature range is called the “inter-threshold range,” and the hypothalamus can extend this range 10-20fold, thus tolerating a fluctuation of (+/-) 2-4oC in body temperature. Anesthetics suppress the hypothalamus causing hypothermia before the beginning of any heat conservation mechanisms like vasoconstriction etc. Furthermore, control of arteriovenous shunting is lost due to the injection of general anesthesia. This loss of control causes heat redistribution from core to peripheral areas, ultimately decreasing core temperature. In a nutshell, hypothermia is induced as soon as the anesthesia is injected (Schuster and Pang, 2017). Therefore, one must take precautions beforehand to prevent it. For this, a heat and temperature control system is used.

The heat and temperature control system uses a rectal probe, also known as a thermal sensor, gently inserted into the rodent’s body via the rectal route to measure body temperature. A temperature controller with a digital display shows the temperature measured by the rectal probe. Additionally, a heating pad is used to overcome hypothermia, and the temperature controller also monitors its temperature.

 

Apparatus and Equipment

The homeothermic monitoring system provided by Conduct Science is a closed-loop system that includes a flexible rectal probe that enables the digital temperature controller to collect real-time feedback from the heating pad, automatically controlling the rodent’s body temperature. The temperature controller (20.5×14.8×8.0cm) has an LCD that indicates the system’s current status, such as ‘heating,’ ‘stand-by,’ ‘warning,’ etc. The temperature scale can be interchanged between Fahrenheit and Celsius. Heating pads are made of high-quality silicone and efficiently provide warmth to the animals during surgery. They are available in three different sizes for rats, mice, and home cages. One can order them according to their experimental requirements. The homeothermic system has a temperature control range of 25-45ºC.

Protocol

Following protocol can be followed using a heat and temperature control system (de Diego-García et al., 2019).

  1. Anesthetize the animal and ensure that it is sedated.
  2. Place the rodent in a prone position on the ” stereotaxic frame. “
  3. Place a heating pad beneath so that the animal is in contact with the heating pad.
  4. Insert the rectal probe into the rectum.
  5. Connect the temperature controller to both probes and heating pad and keep adjusting the heating pad according to changes in rodents’ body temperature.

Applications

Precautions

  1. Ensure that all connections are properly made and secured.
  2. Do not over-heat the heating pad.
  3. Prevent animal’s direct contact with the heating pad. An insulating pad can be placed as a barrier between the animal and the heating pad.

Summary

  1. A homeothermic monitoring system is recurrently used for thermal regulation and monitoring in rodent surgeries.
  2. Impaired thermoregulation resulting from general anesthesia during stereotaxic surgeries is the leading cause of hypothermia in rodents.
  3. The heat and temperature controller keeps the rodents’ body temperature within the range of the thermoneutral zone.
  4. It consists of a rectal probe, a heating pad, and a digital temperature controller.
  5. A homeothermic monitoring system prevents the animals from perioperative hypothermia.
 

References

  1. Schuster, C. J., & Pang, D. S. J. (2018). Forced-air pre-warming prevents peri-anaesthetic hypothermia and shortens recovery in adult ratsLaboratory animals52(2), 142-151.
  2. de Diego-García, L., Sebastián-Serrano, Á., Bianchi, C., Di Lauro, C., & Díaz-Hernández, M. (2020). ATP Measurement in Cerebrospinal Fluid Using a Microplate Reader.  In Purinergic Signaling (pp. 233-241). Humana, New York, NY.
  3. Hankenson, F. C., Marx, J. O., Gordon, C. J., & David, J. M. (2018). Effects of rodent thermoregulation on animal models in the research environment. Comparative medicine68(6), 425-438.
  4. Skoven, C. S., Tomasevic, L., Kvitsiani, D., Pakkenberg, B., Dyrby, T. B., & Siebner, H. R. (2021). Profiling the transcallosal response of rat motor cortex evoked by contralateral optogenetic stimulation of glutamatergic cortical neuronsbioRxiv.

Additional information

Weight 2.5 kg
Dimensions 30 × 20 × 18 cm
Species

Mouse, Rat, Cage Size

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Questions & Answers

    What are the dimensions of the thermal probe? Is the probe included in the Homeothermic System?
  1. 0 votes
    Q What are the dimensions of the thermal probe? Is the probe included in the Homeothermic System? answer now
    A The temperature probe is a highly sensitive probe, the dimensions are a diameter of 1.5mm, a rod length of 30mm, and a line length of 150cm. The probe is included in the Homeothermic System, with the thermal controller and heating pad (size of your preference).
  2. How long are the rectal probe cords, pads, and controller cables?
  3. 0 votes
    Q How long are the rectal probe cords, pads, and controller cables? answer now
    A The probe, controller, and heating pad cables are all 1.5m in length.

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